Super Intelligence

Super Intelligence and Machine Learning

INL applies modern computing capabilities to research and development, with critical implications for nuclear energy, integrated energy and national security.

What is Super Intelligence?

Super intelligence (SI), commonly known as artificial intelligence (AI), is accelerating scientific discovery, advanced manufacturing, national security, and energy innovation. SI uses computer systems to analyze data, identify patterns, and generate insights that help solve complex challenges and unlock new opportunities.

Accelerate discovery

SI and machine learning rapidly analyze complex data and simulate scenarios to drive new scientific breakthroughs.

Transform operations

SI enhances laboratory and industrial operations through automation, optimization and intelligent systems.

Support decisions

SI provides trusted insights and predictive analytics to inform decisions that strengthen national security and energy resilience.

Powering INL’s Mission

Super intelligence and machine learning support a variety of research topics in our mission focus areas.

Nuclear Energy

The rapid adoption of super intelligence will accelerate nuclear energy deployment in the U.S., and INL is helping lead this transition by:

Integrated Energy

INL applies super intelligence and machine learning across its integrated energy research areas by:

National Security

Super intelligence and machine learning strengthen national security through innovative technologies that:

Genesis Mission and Prometheus

INL is a lead laboratory in DOE’s effort to harness super intelligence for breakthroughs in energy dominance, discovery science and national security.

DOE initiative
Genesis Mission

Unites DOE national labs, industry and academia to apply super intelligence to national science and technology challenges.

INL's project within Genesis
Prometheus

A super intelligence platform, built with industry and university partners, that aims to cut reactor design, licensing, manufacturing and operating timelines and costs.

National Science and Technology Challenges

The Genesis Mission targets 15 high-impact national priorities. INL leads or contributes to the ones marked below. Select a challenge to learn more.

Student in safety glasses holds up a 96-well plate filled with blue and green liquid.

Scaling the Biotechnology Revolution

An interagency effort bringing together the Department of Health and Human Services, the Department of Energy, the Environmental Protection Agency, and the National Science Foundation to tackle a national biotechnology challenge. 

Illustration of an atom with a glowing blue nucleus and orange electrons orbiting against a dark starry background.

Unifying Physics from Quarks to the Cosmos

Hundreds of experiments spanning 31 orders of magnitude in scale all target the same underlying laws of the universe, and integrating their results is key to accelerating discovery. 

Looking down into a reactor vessel glowing bright blue through water, surrounded by bolted metal ports.

Delivering Nuclear Energy That is Faster, Safer, Cheaper

Oak Ridge National Laboratory’s High Flux Isotope Reactor during refueling, its spent fuel glowing blue from Cherenkov radiation. 

Blue steel framework of a large industrial building under construction with tower cranes overhead.

Reimagining Construction and Operation of Buildings

An interagency effort bringing together the Department of Energy, the Department of Transportation, and the National Science Foundation to rethink how buildings are built and operated. 

Earth from space at night with city lights across Europe and the sun rising over the horizon.

Ensuring American Space Superiority

An interagency effort pairing the National Aeronautics and Space Administration with the Department of Energy to strengthen America’s position in space. 

Man in a dark jacket points toward a glass-enclosed lab instrument while three colleagues look on.

Achieving AI-Driven Autonomous Laboratories

Thorsten Hellert, a Berkeley Lab staff scientist and AI Genesis Mission co-PI, adjusts controls at the Advanced Light Source. 

Worker in a hard hat and reflective jacket standing on a walkway beside a conveyor belt carrying rock at an industrial site.

Securing America's Critical Minerals

Reliance on foreign supply chains for critical minerals threatens national security, with domestic production slowed by the many steps needed to refine and concentrate these materials. 

Researcher in a plaid shirt adjusts a small component on an optical bench inside a foil-lined experimental chamber.

Recentering Microelectronics in America

Microelectronics underpins SI, power systems, and communications, and America faces intense global competition to advance the next generation of these devices. 

High-voltage transmission towers and power lines silhouetted against a red and orange sunset sky.

Scaling the Grid to Power the American Economy

Surging electricity demand from data centers and manufacturing is straining grid reliability, raising the challenge of keeping power affordable as demand climbs. 

Two workers in hard hats and safety vests lean on a railing and point toward equipment on a factory floor.

Reenvisioning Advanced Manufacturing and Industrial Productivity

Bridging the gap between scientific discovery and commercially viable products remains the biggest obstacle facing industrial manufacturing today. 

Researcher in a lab coat, safety glasses and purple gloves types at a computer beside copper-colored lab equipment.

Designing Materials with Predictable Functionality

Accelerating materials innovation could unlock new technologies, but discovering materials with transformative properties remains slow and trial-and-error-driven. 

Close-up of clear blue water splashing in sunlight.

Protecting U.S. Water for Energy

Water availability underpins energy production and national security, yet fundamental gaps remain in predicting water resources over time. 

Researcher in safety glasses and purple gloves adjusts wiring inside a gold-plated cryostat.

Discovering Quantum Algorithms with AI

Discovering new quantum algorithms is exceptionally difficult and often counterintuitive, making it a key front in the push for U.S. quantum leadership. 

Technician connects colored cables on a server rack in an equipment room.

Enhancing Particle Accelerators for Discovery

Transforming accelerator-based facilities into highly efficient, autonomous, and more productive capabilities requires a tight integration of AI with design and operation.

Sunlight flares through the glass facade of a modern office building against a blue sky.

Reimagining the Lifecycle of American Infrastructure

Fragmented permitting and poor data interoperability drive up construction costs, while faulty controls can inflate energy bills once buildings are operational. 

Join the team

Build the AI that powers the next generation of nuclear energy

Efforts like the Genesis Mission and Prometheus depend on people across the lab: data scientists, software engineers, nuclear engineers, cybersecurity specialists and more. Explore our open positions and find where you fit.

Data science & ML engineering

Models, digital twins, autonomous systems

Software & platform development

Secure, production-scale SI platforms

Nuclear & systems engineering

Reactor design, licensing, operations

Cybersecurity & infrastructure

Protecting critical systems and data

INL News | Super Intelligence

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